Olfactory Esthesioneuroblastoma

A malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., SIADH, Cushing Syndrome). It has a high propensity for multiple local recurrences and bony metastases. (From Holland et al., Cancer Medicine, 3rd ed, p1245; J Laryngol Otol 1998 Jul;112(7):628-33)

Also Known As:

Esthesioneuroblastoma; Esthesioneuroblastoma, Olfactory; Esthesioneuroblastoma, Paranasal Sinus-Nasal Cavity; Aesthesioneuroblastomas; Esthesioneuroblastoma, Paranasal Sinus Nasal Cavity; Esthesioneuroblastomas; Esthesioneuroblastomas, Olfactory; Neuroblastomas, Olfactory; Olfactory Esthesioneuroblastomas; Olfactory Neuroblastomas; Paranasal Sinus Nasal Cavity Esthesioneuroblastoma; Aesthesioneuroblastoma; Neuroblastoma, Olfactory; Olfactory Neuroblastoma; Paranasal Sinus-Nasal Cavity Esthesioneuroblastoma

Neoplasms: 1324753
- Neoplasms by Histologic Type: 2
  - Germ Cell and Embryonal Neoplasms: 4454
    - Neuroectodermal Tumors: 217
      - Neuroepithelial Neoplasms: 412
        Primitive Neuroectodermal Tumors: 1966
        Peripheral Primitive Neuroectodermal Tumors: 116
        Neuroblastoma: 26260
        Olfactory Esthesioneuroblastoma: 393
  - Glandular and Epithelial Neoplasms: 439
    - Neuroepithelial Neoplasms: 412
      - Primitive Neuroectodermal Tumors: 1966
        Peripheral Primitive Neuroectodermal Tumors: 116
        Neuroblastoma: 26260
        Olfactory Esthesioneuroblastoma: 393
  - Nerve Tissue Neoplasms: 1
    - Neuroectodermal Tumors: 217
      - Neuroepithelial Neoplasms: 412
        Primitive Neuroectodermal Tumors: 1966
        Peripheral Primitive Neuroectodermal Tumors: 116
        Neuroblastoma: 26260
        Olfactory Esthesioneuroblastoma: 393
Nervous System Diseases: 14178
- Cranial Nerve Diseases: 554
  - Olfactory Nerve Diseases
    - Olfactory Esthesioneuroblastoma: 393

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